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Magnetic resonance imaging of rat brain following in vivo disruption of the cerebral vasculature

โœ Scribed by Norman, Andrew B.; Bertram, Karl J.; Thomas, Stephen R.; Pratt, Ronald G.; Samaratunga, R.C.; Sanberg, Paul R.


Book ID
124106721
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
1023 KB
Volume
26
Category
Article
ISSN
0361-9230

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The neurotoxicity of intravenously injected Gadolinium (Gd) complexes to rats with disrupted blood-brain barrier (BBB) was evaluated. After disruption of the BBB by infusion of mannitol solution, one of several contrast agents tested was injected intravenously at a dose of 1 or 3 mmol Gd/kg, and neu