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Magnetic resonance imaging of melanoma metastases in a clinical relevant human melanoma xenograft scid mouse model

✍ Scribed by Anka Thies; Kersten Peldschus; Harald Ittrich; Gerhard Adam; Peter Altevogt; Christoph Wagener; Udo Schumacher


Book ID
116334985
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
647 KB
Volume
274
Category
Article
ISSN
0304-3835

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## Abstract Cancer therapy involving blood‐borne macromolecular therapeutic agents often fails, owing to inadequate macromolecule uptake in malignant tissue. The transvascular and interstitial transport of a 19 kDa linear molecule (NC22181 or poly‐[Gd‐DTPA]‐co‐[1,6‐diaminohexane]) was studied in th