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Magnetic Resonance Imaging of Alzheimer's Pathology in the Brains of Living Transgenic Mice: A New Tool in Alzheimer's Disease Research

✍ Scribed by Jack, C. R.; Marjanska, M.; Wengenack, T. M.; Reyes, D. A.; Curran, G. L.; Lin, J.; Preboske, G. M.; Poduslo, J. F.; Garwood, M.

Book ID
118136961
Publisher
SAGE Publications
Year
2007
Tongue
English
Weight
416 KB
Volume
13
Category
Article
ISSN
1073-8584

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## Abstract One of the cardinal pathologic features of Alzheimer's disease (AD) is the formation of senile, or amyloid, plaques. Transgenic mice have been developed that express one or more of the genes responsible for familial AD in humans. Doubly transgenic mice develop β€œhuman‐like” plaques, prov