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Magnetic field modulation of receptor binding

✍ Scribed by Catherine Chiles; Edward Hawrot; John Gore; Robert Byck

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
304 KB
Volume
10
Category
Article
ISSN
0740-3194

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✦ Synopsis

Although it is widely held that the magnetic fields encountered during magnetic resonance imaging (MRI) and other procedures have no discernible effect on biological systems, we find that at early times of incubation, the amount of binding ofthe neurotoxin, a-bungarotoxin, to nicotinic acetylcholine receptor is significantly reduced in a constant 2.0-T magnetic field. This finding suggests that steady magnetic fields can directly affect the functional activity of biologically important macromolecules, in this particular case a neurotransmitter receptor. o 1989 Academic press, Inc.

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