Magnetic Alignment of Duplex and Quadruplex DNAs

✍ Scribed by Hsiang Chuan Kung; Ke Yu Wang; Igor Goljer; Philip H. Bolton

• Book ID: 102596968
• Publisher: Elsevier Science
• Year: 1995
• Tongue: English
• Weight: 67 KB
• Volume: 109
• Category: Article
• ISSN: 1064-1866
• DOI: 10.1006/jmrb.1995.9987

✦ Synopsis

Anisotropic diamagnetic molecules in isotropic solution to the magnetic alignment axis, and R is the length of the C-H bond. can be partially aligned by a sufficiently large magnetic field (1). In the liquid state, the magnetic-field-induced alignment

The heteronuclear couplings were determined at natural abundance by use of standard heteronuclear correlation tech-is in competition with Brownian motion and only very small alignments are typically observed (1). Magnetic alignment niques on a 3 mM sample of the DNA duplex formed by d(C 1 G 2 C 3 G 4 A 5 A 6 T 7 T 8 C 9 G 10 C 11 G 12 ) 2 with detection of the can be detected by observation of changes in apparent coupling constants or by the splitting of a quadrupolar resonance proton signals without C decoupling and on a sample of d(G