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Magnesium therapy in massive digoxin intoxication

✍ Scribed by James H French; Richard G Thomas; Andrew P Siskind; Michael Brodsky; Lloyd T Iseri


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
495 KB
Volume
13
Category
Article
ISSN
1097-6760

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✦ Synopsis


A potentially fatal case of massive digitalis intoxication is presented. Recurrent ventricular fibrillation failed to respond to lidocaine or phenytoin, but responded dramatically to magnesium sulfate infusion. A review of the literature and previous clinical studies, as well as the case reported here, appears to indicate that magnesium sulfate given intravenously in adequate quantities (2 to 3 g in one minute followed by 2 g/h for 4 to 5 h) is effective in controlling ventricular irritability caused by toxic levels of digitalis preparations.


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Accidental digitalis ingestion in children is a rare, but potentially life-threatening emergency. We report the case of a 2 10/12-year-old boy with accidental ingestion of 6 mg beta-Acetyl-digoxin. Soon after admission, the boy developed sinus bradycardia, SA and AV-block, of increasing severity wit