Ma'eganedin A, a new manzamine alkaloid from Amphimedon sponge
β Scribed by Masashi Tsuda; Daisuke Watanabe; Jun'ichi Kobayashi
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 213 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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AbstractΓA crude extract of a marine sponge showed initial inhibitory bioactivities in a yeast assay for inhibitors of methionine aminopeptidase-2 (Met AP-2). Bioassay-directed fractionation indicated that the activity was concentrated in the CH 2 Cl 2 -soluble fraction, and chromatography on silica