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Macroscopic and microscopic assessments of disease burden by MRI in multiple sclerosis: Relationship to clinical parameters

✍ Scribed by Claudio Gasperini; Mark A. Horsfield; John W. Thorpe; Desmond Kidd; Gareth J. Barker; Paul S. Tofts; David G. Macmanus; Alan J. Thompson; David H. Miller; W. Ian McDonald

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
580 KB
Volume
6
Category
Article
ISSN
1053-1807

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Quantitative volumetric magnetization tr
Quantitative volumetric magnetization transfer analysis in multiple sclerosis: Estimation of macroscopic and microscopic disease burden
✍ Mark A. van Buchem; Joseph C. McGowan; Dennis L. Kolson; Marcia Polansky; Robert 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 574 KB

## Abstract Magnetization transfer imaging (MTI) has been shown to be sensitive to both macroscopic and microscopic disease in multiple sclerosis (MS). In this study three‐dimensional MTI was used to estimate the global burden of disease in large volumes of brain tissue. MTI was performed in 15 MS