β-Defensins chemoattract macrophages and
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Afsaneh Soruri; Jasmin Grigat; Ulf Forssmann; Joachim Riggert; Jörg Zwirner
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Article
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2007
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John Wiley and Sons
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English
⚖ 490 KB
## Abstract β‐Defensins are natural peptide antibiotics whose immunomodulatory functions are poorly understood. In the present study, macrophages were found to migrate to human β‐defensins (HBD)‐1 to ‐4 using Gα~i~ proteins as well as MAPK ERK, p38 and JNK as signal transducers. In addition, mast c