Macrophage-secreted prostaglandin E2 potentiates immune complex-induced B cell unresponsiveness

Secretion of thromboxane B2 and prostagl

Secretion of thromboxane B2 and prostaglandin E2 by guinea-pig lung cells isolated by centrifugal elutriation and by macrophages obtained by bronchoalveolar lavage

✍ J.P. Pelé; C. Robidoux; P. Sirois 📂 Article 📅 1989 🏛 Elsevier 🌐 English ⚖ 810 KB

Guinea-pig lung cells were partially purified by an elutriation technique after enzymatic digestion of the lung. Eight fractions were obtained and the cell content of each fraction was analysed by staining and by electron microscopy. After stimulation with selected agonists, the secretion of eicosan