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MACROPHAGE MIGRATION INHIBITORY FACTOR INCREASES MMP-2 ACTIVITY IN DU-145 PROSTATE CELLS

✍ Scribed by Katherine Meyer-Siegler

Book ID
115596511
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
196 KB
Volume
12
Category
Article
ISSN
1043-4666

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## Abstract Transforming growth factor ß (TGFß) is a paracrine mediator of prostate epithelial cell apoptosis. In rodents, castration induces production of TGFβ by stromal cells, which leads to apoptosis of epithelial cells. To identify potential mediators of this cell death pathway, we developed a