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Macrophage migration inhibitory factor and development of type-1 diabetes in non-obese diabetic mice

✍ Scribed by Jörg Bojunga; Klaus Kusterer; Michael Bacher; Ralf Kurek; Klaus-Henning Usadel; Heiner Renneberg

Book ID
117700646
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
534 KB
Volume
21
Category
Article
ISSN
1043-4666

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## Abstract ## Background Heparanase is an endo‐β‐D‐glucuronidase that cleaves heparan sulfate saccharide chains. The enzyme promotes cell adhesion, migration and invasion, and was shown to play a significant role in cancer metastasis and angiogenesis. ## Methods The present study focuses on the