Macrophage migration inhibitory factor: An emerging therapeutic target in rheumatoid arthritis
β Scribed by Eric F. Morand; Richard Bucala; Michelle Leech
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 86 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Objective To study the capacity of macrophage migration inhibitory factor (MIF) to regulate proliferation, apoptosis, and p53 in an animal model of rheumatoid arthritis (RA) and in fibroblastβlike synoviocytes (FLS) from humans with RA. ## Methods Antigenβinduced arthritis (AIA) w
## Abstract ## Objective Previous studies have demonstrated that neutralization of macrophage migration inhibitory factor (MIF) by antiβMIF antibodies decreases joint inflammation and destruction in a type II collagenβinduced arthritis model in mice. The aim of this study was to develop and descri
## Abstract ## Objective Chondromodulin I (ChMβI), a cartilage matrix protein, promotes the growth and proteoglycan synthesis of chondrocytes. However, it also inhibits angiogenesis. Since ChMβI is expressed not only in cartilage, but also in the thymus, we investigated the modulation of T cell fu