Macrophage inflammatory protein-1α in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological diseases
✍ Scribed by Ryuji Miyagishi; Seiji Kikuchi; Toshiyuki Fukazawa; Kunio Tashiro
- Book ID
- 118932197
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 476 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0022-510X
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Cerebrospinal fluid (CSF) from 105 patients was analyzed by radioimmunoassay for the presence of material cross-reactive with peptide 89-169 of bovine myelin basic protein (BP). In a group of 72 multiple sclerosis patients, 52 showed higher BP content than the control group, i.e. more than 2 ng/ml C
We studied paired cerebrospinal fluid (CSF) and peripheral blood (PB) samples from 18 inactive multiple sclerosis (MS) patients and 10 with non-inflammatory neurological diseases. By means of a dual-colour cytofluorimetric micromethod we were able to count 1500 cells on average in each CSF sample. W