Macrophage activation in rat models of inflammation and arthritis: Systemic activation precedes arthritis induction and progression
β Scribed by William J. Johnson; Katharine A. Muirhead; Paul C. Meunier; Bart J. Votta; Thomas C. Schmitt; Michael J. Dimartino; Nabil Hanna
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 833 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
HLH Ο hemophagocytic lymphohistiocytosis; MAS Ο macrophage activation syndrome; CNS Ο central nervous system; SGOT Ο serum glutamate oxaloacetate transaminase; SGPT Ο serum glutamate pyruvate transaminase; PT Ο prothrombin time; PTT Ο partial thromboplastin time. β Based on refs. 24 and 59. β‘ Based
## Abstract The aberrant induction of proinflammatory cytokines is considered to be crucial in the pathogenesis of systemic juvenile idiopathic arthritis and adultβonset Still's disease. Interleukinβ18 (ILβ18) in particular has been reported to be a candidate for the key cytokine in both diseases;