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Macromolecular Size-and-Shape Distributions by Sedimentation Velocity Analytical Ultracentrifugation

✍ Scribed by Brown, Patrick H.; Schuck, Peter


Book ID
119920244
Publisher
Biophysical Society
Year
2006
Tongue
English
Weight
600 KB
Volume
90
Category
Article
ISSN
0006-3495

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Sedimentation velocity analytical ultracentrifugation (SV-AUC) has found application in the biopharmaceutical industry as a method of detecting and quantifying protein aggregates. While the technique offers several advantages (i.e., matrix-free separation and minimal sample handling), its results ex