Macromolecular Protein Complexes: Structure and Function

✍ Scribed by J. Robin Harris, Jon Marles-Wright (eds.)

Publisher: Springer International Publishing
Year: 2017
Tongue: English
Leaves: 571
Series: Subcellular Biochemistry 83
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This volume of the established Subcellular Biochemistry series presents 20 chapters dealing with a broad range of interesting protein complexes. It will enable researchers to readily appreciate the major contribution from both X-ray crystallography and cryo-electron microscopy in this field of study.

The biological significance of these structural studies is emphasised throughout the book. The diversity of the material included here indicates the breadth of this field and the tremendous progress that has been made in recent years.

The book is directed primarily to advanced students and researchers in structural biology, and others in the biochemical sciences. It will be supplemented by other related books within the Subcellular Biochemistry series. One of the Editors (JM-W) is actively involved in structural biology and the other (JRH), as a retired academic and the Series Editor of Subcellular Biochemistry, has long experience at editing multi-author books.

✦ Table of Contents

Front Matter....Pages i-viii
Structure and Function of the Stressosome Signalling Hub....Pages 1-41
The Canonical Inflammasome: A Macromolecular Complex Driving Inflammation....Pages 43-73
The Ferritin Superfamily....Pages 75-102
Antibody Recognition of Immunodominant Vaccinia Virus Envelope Proteins....Pages 103-126
The Peroxiredoxin Family: An Unfolding Story....Pages 127-147
α2-Macroglobulins: Structure and Function....Pages 149-183
The Structure and Function of the PRMT5:MEP50 Complex....Pages 185-194
Symmetry-Directed Design of Protein Cages and Protein Lattices and Their Applications....Pages 195-224
Structure and Function of RNA Polymerases and the Transcription Machineries....Pages 225-270
Dihydrodipicolinate Synthase: Structure, Dynamics, Function, and Evolution....Pages 271-289
“Pyruvate Carboxylase, Structure and Function”....Pages 291-322
Cullin-RING E3 Ubiquitin Ligases: Bridges to Destruction....Pages 323-347
The Ccr4-Not Complex: Architecture and Structural Insights....Pages 349-379
Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes....Pages 381-412
D-Glyceraldehyde-3-Phosphate Dehydrogenase Structure and Function....Pages 413-453
Protein Complexes in the Nucleus: The Control of Chromosome Segregation....Pages 455-481
GroEL and the GroEL-GroES Complex....Pages 483-504
The Aminoacyl-tRNA Synthetase Complex....Pages 505-522
The Pyruvate Dehydrogenase Complex and Related Assemblies in Health and Disease....Pages 523-550
Structure and Assembly of Clathrin Cages....Pages 551-567
Back Matter....Pages 569-572

✦ Subjects

Protein Science

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