𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Macromolecular monomers for the synthesis of hydrogel niches and their application in cell encapsulation and tissue engineering

✍ Scribed by Charles R. Nuttelman; Mark A. Rice; Amber E. Rydholm; Chelsea N. Salinas; Darshita N. Shah; Kristi S. Anseth

Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
625 KB
Volume
33
Category
Article
ISSN
0079-6700

No coin nor oath required. For personal study only.

✦ Synopsis

Hydrogels formed from the photoinitiated, solution polymerization of macromolecular monomers present distinct advantages as cell delivery materials and are enabling researchers to three-dimensionally encapsulate cells within diverse materials that mimic the extracellular matrix and support cellular viability. Approaches to synthesize gels with biophysically and biochemically controlled microenvironments are becoming increasingly important, and require strategies to control gel properties (e.g., degradation rate and mechanism) on multiple time and size scales. Furthermore, biological responses of gel-encapsulated cells can be promoted by hydrogel degradation products, as well as by the release of tethered biologically relevant molecules.

📜 SIMILAR VOLUMES

A study on the influence of biocompatibl
A study on the influence of biocompatible composites with bioactive ligands toward their effect on cell adhesion and growth for the application in bone tissue engineering
✍ Stefanie Roeker; Stefanie Böhm; Solvig Diederichs; Franziska Bode; Antje Quade; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB 👁 2 views

## Abstract The aim of this study was the transformation of the macroporous zirconium dioxide ceramic Sponceram® into a biomimetic composite material. To enhance the adhesion of cells and to induce their differentiation into osteoblasts poly‐L‐lysine and BMP‐2 were coupled to polymers and copolymer

The effect of cell density on the matura
The effect of cell density on the maturation and contractile ability of muscle derived cells in a 3D tissue-engineered skeletal muscle model and determination of the cellular and mechanical stimuli required for the synthesis of a postural phenotype
✍ V. Mudera; A.S.T. Smith; M.A. Brady; M.P. Lewis 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 959 KB

The successful engineering of a truly biomimetic model of skeletal muscle could have a significant impact on a number of biomedical disciplines. Although a variety of techniques are currently being developed, there is, as of yet, no widely available and easily reproducible culture system for the syn