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Macrolide antibiotics induce apoptosis of human peripheral lymphocytes in vitro

✍ Scribed by Yuji Ishimatsu; Jun-Ichi Kadota; Tetsuji Iwashita; Towako Nagata; Hiroshi Ishii; Chieko Shikuwa; Hideyuki Kaida; Hiroshi Mukae; Shigeru Kohno


Book ID
119258941
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
221 KB
Volume
24
Category
Article
ISSN
0924-8579

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We have recently reported that the tricyclic antidepressants (TCAs) imipramine, clomipramine, and citalopram induce apoptosis in human peripheral lymphocytes. This system is well suited for studies on the pathophysiology/physiology of apoptosis regulation. Apoptosis was determined using both DNA gel