N-Boc-u-msylsarcosine ethyl ester (3) reacts under neutral conditions either with allylic carbonates or with vinyloxinme in the presence of a catalytic amount of Pd(PPh3) 4 and dppe (5 mol%) to give regio-and stereoselectively the corresponding allylated products $ and 6, respectively. Reductive des
Macroheterocycles. 5. Synthesis of macrocyclic amido esters and amido thioesters on the basis of derivatives of α-hydroxy and α-mercapto acids
✍ Scribed by N. G. Luk'yanenko; A. V. Bogat-skii; Yu. A. Popkov
- Book ID
- 112744487
- Publisher
- Springer US
- Year
- 1980
- Tongue
- English
- Weight
- 325 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0009-3122
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Reactions of ethyl 2-diazoacetate with aldehydo sugars and monosaccharide derivatives in their hemiacetal form are reported. The use of diethyl zinc led to an improvement of yields and shorter reaction times compared with neutral conditions as previously described. The resulting products represent p