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Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids

✍ Scribed by Blackwell, Geoffrey J.; Carnuccio, Rosa; Rosa, Massimo Di; Flower, Roderick J.; Parente, Luca; Persico, Paola


Book ID
109719643
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
329 KB
Volume
287
Category
Article
ISSN
0028-0836

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The action of theophylline on the uptake of alpha-aminoisobutyric acid (AIB; an indicator of anti-inflammatory potency) stimulated by the glucocorticoid, dexamethasone, in cultured rat fibroblast monolayers was evaluated. Theophylline alone (0.1 m m) did not show significant activity (3314+/-27 cpm)