Macro-branched cell-penetrating peptide design for gene delivery
β Scribed by Zhihui Liu; Moyi Li; Dafu Cui; Jian Fei
- Book ID
- 113690759
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 471 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0168-3659
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background To overcome extracellular barriers in gene therapy, controlled release technology has been adapted to protect DNA from degradation and maintain elevated DNA concentration. Although cellβpenetrating peptides (CPPs) have been widely utilized to enhance the transfection effi
## Abstract Novel classes and applications of cellβpenetrating peptides (CPPs) are being constantly discovered since they were first identified 2 decades ago. These short cationic peptides (nanomolecules) either by covalent binding or by noncovalent binding can traverse cell membranes and deliver a