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MAC (morphology antibody chromosomes) technique for in situ chromosome preparations

✍ Scribed by Sakari Knuutila


Book ID
104661297
Publisher
Springer
Year
1991
Tongue
English
Weight
175 KB
Volume
87
Category
Article
ISSN
0340-6717

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✦ Synopsis


In an article on the i m m u n o p h e n o t y p i n g of aneuploid cells (Knuutila and Teerenhovi 1989), we described the application of the method k n o w n as M A C (morphology antibody chromosomes) not only to cytospin preparations but also to in situ c h r o m o s o m e preparations. Thus, the technique recently reported by H e n n et al. (1990) is not


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✍ Sakari Knuutila; Riitta Alitalo; Tapani Ruutu πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 476 KB

We present a patient with acute lymphatic leukemia, eosinophilia, and a 5; I4-translocation, a rare but well-documented condition. In order to clarify whether granulocytes were involved in the disease, we applied the MAC (Morphology-Antibody-Chromosomes) technique to samples of the bone marrow and,