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MAC and Bcl-2 family proteins conspire in a deadly plot

โœ Scribed by Laurent M. Dejean; Shin-Young Ryu; Sonia Martinez-Caballero; Oscar Teijido; Pablo M. Peixoto; Kathleen W. Kinnally

Book ID
113484499
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
505 KB
Volume
1797
Category
Article
ISSN
0005-2728

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B cell lymphoma gene-2 (Bcl-2) is the prototypic member of a growing family of proteins that play evolutionarily conserved, key regulatory roles in apoptosis. The Bcl-2 family members are characterized by the presence of one or more Bcl-2 homology domains and are comprised of both the prosurvival an