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M2046 Bile Acids Cause Relaxation of Lower Esophageal Sphincter Through G Protein-Coupled Bile Acid Receptors

โœ Scribed by Huang, Shih-Che


Book ID
122907252
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
98 KB
Volume
138
Category
Article
ISSN
0016-5085

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The G-Protein-coupled bile acid receptor
โœ Yan-Dong Wang; Wei-Dong Chen; Donna Yu; Barry M. Forman; Wendong Huang ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 934 KB

Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 also displays strong attenuation of macrophage reactivity in vitro, but the physiological roles of TGR5 in inflammatory response, and its mechanism, is unk