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M1803 Differential Degradation of Anti-Tumor Necrosis Factor-α Agents by Matrix Metalloproteinase-12 in Inflammatory Bowel Disease

✍ Scribed by Biancheri, Paolo; Di Sabatino, Antonio; Rovedatti, Laura; Ahmad, Nadja; Corazza, Gino Roberto; MacDonald, Thomas T.


Book ID
123135953
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
47 KB
Volume
138
Category
Article
ISSN
0016-5085

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## Background: Previous studies have shown an upregulation of matrix metalloproteinases (mmps) in intestinal tissue of patients with inflammatory bowel disease (ibd) and significant clinical improvement after administration of the anti-tnf-a antibody infliximab. the aims of our study were to determ