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M1702 The Transcription Factor SPDEF Inhibits Proliferation of Colon Tumors in Mice

✍ Scribed by Noah, Taeko K.; Shroyer, Noah F.

Book ID
123565970
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
82 KB
Volume
138
Category
Article
ISSN
0016-5085

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## Abstract We evaluated RS5444, a thiazolidinedione high affinity PPARΞ³ agonist, for the ability to inhibit colon carcinogenesis in azoxymethane (AOM)‐treated mice. In our initial experiment, mice were treated with RS5444 during AOM treatment, and the drug was withdrawn 12 weeks after the last inj