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M1226 Fecal Osteoprotegerin Predicts the Need for Second Line Therapy in Hospitalized Children With Ulcerative Colitis

โœ Scribed by Sylvester, Francisco A.; Turner, Dan; Draghi, Andrew; Uuosoe, Krista; MacLernon, Robin A.; Griffiths, Anne M.

Book ID
123370719
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
45 KB
Volume
138
Category
Article
ISSN
0016-5085

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๐Ÿ“œ SIMILAR VOLUMES

Fecal osteoprotegerin may guide the intr
Fecal osteoprotegerin may guide the introduction of second-line therapy in hospitalized children with ulcerative colitis
โœ Francisco A. Sylvester; Dan Turner; Andrew Draghi II; Krista Uuosoe; Robin McLer ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 105 KB

Background: Osteoprotegerin (OPG) is increased in inflamed colonic mucosa and has a role in immune regulation and apoptosis resistance. Fecal OPG may be useful in predicting corticosteroid resistance in hospitalized children with severe ulcerative colitis (UC). We aimed to determine whether fecal OP