M1 muscarinic agonists protect PC12M1 cells from growth factor deprivation and β-amyloids-induced apoptosis

Dual inhibition of protein phosphatase-1

Dual inhibition of protein phosphatase-1/2A and calpain rescues nerve growth factor-differentiated PC12 cells from oxygen-glucose deprivation-induced cell death

✍ Takayuki Nakajima; Takashi Wakasa; Yasunobu Okuma; Osamu Inanami; Yasuyuki Nomur 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 468 KB

## Abstract In the present study, we examined how the cell survival signaling via cyclic AMP‐responsive element binding protein (CREB) and Akt, and the cell death signaling via cystein proteases, calpain and caspase‐3, are involved in oxygen‐glucose deprivation (OGD) followed by reoxygenation (OGD/