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M1 and M2 Muscarinic Receptor Subtypes Regulate Antidepressant-Like Effects of the Rapidly Acting Antidepressant Scopolamine

โœ Scribed by Witkin, J. M.; Overshiner, C.; Li, X.; Catlow, J. T.; Wishart, G. N.; Schober, D. A.; Heinz, B. A.; Nikolayev, A.; Tolstikov, V. V.; Anderson, W. H.; Higgs, R. E.; Kuo, M.- S.; Felder, C. C.

Book ID
126844515
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2014
Tongue
English
Weight
837 KB
Volume
351
Category
Article
ISSN
0022-3565

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The relative selectivity of anticholiner
The relative selectivity of anticholinergic drugs for the M1 and M2 muscarinic receptor subtypes
โœ Dr. Robert E. Burke ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 775 KB

Anticholinergic drugs are used to treat a number of neurologic disorders, inctuding parkinsonism, vestibular disturbances, and dystonia. Traditionally, these drugs have been thought to act in similar fashion, as competitive antagonists at a single class of muscarink receptors, and not to differ sign