M. lepraeinhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression
β Scribed by Zahra Hasan; Mussarat Ashraf; Ali Tayyebi; Rabia Hussain
- Book ID
- 115005586
- Publisher
- BioMed Central
- Year
- 2006
- Tongue
- English
- Weight
- 462 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1471-2180
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
During B- and T-cell ontogeny, extensive apoptosis occurs at distinct stages of development. Agents that increase intracellular levels of cAMP induce apoptosis in thymocytes and mature B cells, prompting us to investigate the role of cAMP signaling in human CD10+ B-precursor cells. We show for the f
## Abstract Salvicine, a novel topoisomerase II inhibitor and a diterpenoid quinone compound, exerts potent __in vitro__ and __in vivo__ antitumor effects. In our study, we show that salvicine effectively kills multidrugβresistant (MDR) sublines, such as K562/A02, KB/VCR and MCFβ7/ADR, and parental
## Abstract __Pseudomonas__ exotoxin (PE)βcontaining immunotoxins (ITs) act by arresting protein synthesis and promoting apoptosis, but the mechanisms of the induced apoptosis and the relationship to protein synthesis inhibition is not well elucidated. We studied these effects in MAβ11 human breast