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Lytic replication of Epstein-Barr virus is controlled by a posttranscriptional regulation mechanism for the immediate early gene BZLF1

โœ Scribed by N. Prang; H. Wolf; F. Schwarzmann


Book ID
112781460
Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
140 KB
Volume
121
Category
Article
ISSN
1432-1335

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The ability of the Epstein-Barr virus (EBV) to avoid lytic replication and to establish a latent infection in B-lymphocytes is fundamental for its lifelong persistence and the pathogenesis of various EBV-associated diseases. The viral immediate-early gene BZLF-1 plays a key role for the induction of