Lyt 1 cells respond to la-bearing macrophages in the murine syngeneic mixed lymphocyte reaction

✍ Scribed by Edmund C. Lattime; Sidney H. Golub; Osias Stutman

• Publisher: John Wiley and Sons
• Year: 1980
• Tongue: English
• Weight: 398 KB
• Volume: 10
• Category: Article
• ISSN: 0014-2980
• DOI: 10.1002/eji.1830100913

✦ Synopsis

Abstract

An autologous mixed lymphocyte reaction has been described in mice and humans in which T cells proliferate following stimulation with syngeneic non‐T cells. This report demonstrates that in the murine syngeneic mixed lymphocyte reaction, the responder cell is an Ly 1^+^, Ly 23^−^, Qa‐1^−^T cell. The stimulator is an la‐bearing macrophage‐like cell.