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Lysosomal membrane fragility and catabolism of cytosolic proteins: evidence for a direct relationship

✍ Scribed by M. N. Moore; A. Viarengo


Book ID
105407538
Publisher
Springer
Year
1987
Tongue
English
Weight
527 KB
Volume
43
Category
Article
ISSN
1420-682X

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When intact platelets are incubated at 37 degrees C with Concanavalin A (ConA), the two major surface membrane proteins GPIIb and III become associated with the Triton-insoluble cytoskeleton. Preincubation of platelets with a variety of metabolic inhibitors, including cytochalasin B, 2-deoxy-D-gluco