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Lysosomal hydrolase activity in chorionic villi and embryonic cells in culture

✍ Scribed by Livia Poenaru; Laetitia Castelnau; Agnès Choiset; Y. Rouquet; F. Thepot

Publisher: Springer
Year: 1985
Tongue: English
Weight: 175 KB
Volume: 69
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00291659

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✦ Synopsis

Fourteen lysosomal enzymes were compared in 20 cultured cell lines from chorionic biopsy and corresponding embryonic tissue after voluntary abortions. Enzymatic expression appears to be similar in cultured cells from both sources with some slightly higher levels for chorionic villi. We stress the importance of culturing chorionic villi especially in the case of enzymes (alpha-L-iduronidase) or diseases (I cell disease) whose expression is unusual in fresh trophoblast tissue.

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