Lysosomal ceramide mediates gemcitabine-induced death of glioma cells
โ Scribed by Claudia A. Dumitru; Ibrahim E. Sandalcioglu; Marek Wagner; Michael Weller; Erich Gulbins
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 309 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0946-2716
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Ceramide is a sphingolipid that has been implicated both in apoptosis and protection from cell death. We show that in both rat cerebellar granule cells and cortical neuronal cultures application of C(2)-ceramide causes cell death in a dose- and time-dependent manner. Similar effects were observed wi
This study examined the effects of full-length p16 gene transfer by recombinant adenovirus on cell growth and on sensitivity to CDDP or ACNU chemotherapies. We developed a recombinant adenovirus expressing the full-length human p16 gene (AxCA-hp16) by the COS-TPC method. AxCA-hp16 was infected into