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Lysophosphatidylcholine increases 3-Hydroxy-3-methylglutaryl-coenzyme A reductase gene expression in CaCo-2 cells

✍ Scribed by LV Muir; E Born; SN Mathur; FJ Field

Book ID
119755335
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
496 KB
Volume
110
Category
Article
ISSN
0016-5085

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## Abstract Elevated 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase expression supports synthesis of prenyl pyrophosphate intermediates required for tumor growth. In this study, the copy number of HMG‐CoA reductase mRNA was determined in solid tumor and leukemic cell lines using competit