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Lysophosphatidic acid stimulates cell proliferation in rat chondrocytes

โœ Scribed by Mi-Kyoung Kim; Ha-Young Lee; Kyoung Sun Park; Eun Ha Shin; Seong Ho Jo; Jeanho Yun; Sung Won Lee; Young Hyun Yoo; Yun-Sik Lee; Suk-Hwan Baek; Yoe-Sik Bae

Book ID
113487758
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
267 KB
Volume
70
Category
Article
ISSN
0006-2952

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Lysophosphatidic acid stimulates phospho
Lysophosphatidic acid stimulates phospholipase D activity and cell proliferation in PC-3 human prostate cancer cells
โœ Chen Qi; Jin-Hyouk Park; Terra C. Gibbs; David W. Shirley; Cynthia D. Bradshaw; ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 325 KB

Phospholipase D (PLD) is activated in mammalian cells in response to a variety of growth factors and may play a role in cell proliferation. Lysophosphatidic acid (LPA) is a bioactive metabolite potentially generated as a result of PLD activation. Two human prostate cancer cell lines, PC-3 and LNCaP,