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Lysophosphatidic Acid (LPA)-Induced Vascular Endothelial Growth Factor (VEGF) by Mesothelial Cells and Quantification of Host-Derived VEGF in Malignant Ascites

✍ Scribed by Akihiro Sako; Joji Kitayama; Dai Shida; Rika Suzuki; Teruyuki Sakai; Hideo Ohta; Hirokazu Nagawa

Book ID: 116701971
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 348 KB
Volume: 130
Category: Article
ISSN: 0022-4804
DOI: 10.1016/j.jss.2005.08.007

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## Abstract Her‐2/__neu__ (__erb__B‐2) oncogene overexpression is associated with increased tumor progression and metastasis. Fatty acid synthase (FAS), the key lipogenic enzyme responsible for the endogenous synthesis of fatty acids, has been shown to be one of the genes regulated by Her‐2/__neu__