Lysophosphatidic acid-induced interleukin-1β expression is mediated through Gi/Rho and the generation of reactive oxygen species in macrophages

N-(4-hydroxyphenyl)retinamide induces ap

N-(4-hydroxyphenyl)retinamide induces apoptosis in human retinal pigment epithelial cells: Retinoic acid receptors regulate apoptosis, reactive oxygen species generation, and the expression of heme oxygenase-1 and Gadd153

✍ William Samuel; R. Krishnan Kutty; Sahrudaya Nagineni; Camasamudram Vijayasarath 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 418 KB

## Abstract __N__‐(4‐hydroxyphenyl)retinamide (4HPR, fenretinide), a retinoic acid (RA) derivative and a potential cancer preventive agent, is known to exert its chemotherapeutic effects in cancer cells through induction of apoptosis. Earlier work from our laboratory has shown that relatively low c