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Lyn kinase both positively and negatively regulates FcεRI-induced mediator release in RBL mast cells

✍ Scribed by Vonakis, Becky Marie; Rotte, Masashi J; Langdon, Jacqueline M; Gibbons, Scott; Dowdy, Matthew; Chichester, Kristin; MacDonald, Susan M


Book ID
123152260
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
275 KB
Volume
109
Category
Article
ISSN
1097-6825

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## Abstract **Background:** Recent studies have demonstrated that c‐Cbl functions as a ubiquitin‐protein ligase toward immune receptors and non‐receptor protein‐tyrosine kinase Syk by facilitating their ubiquitination and subsequent targeting to proteasomes. However, it was not clear whether Src fa