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Lymphopoiesis in the rat. I. The effect of pool size on lymphocyte production

โœ Scribed by W. P. Vaughan; D. D. McGregor

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
924 KB
Volume
80
Category
Article
ISSN
0021-9541

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โœฆ Synopsis

Abstract

A method is described for measuring lymphopoiesis that enables the production of recirculating and nonโ€recirculating small lymphocytes to be estimated simultaneously. Using this technique, experiments were undertaken to determine whether the production of recirculating cells is influenced by the number present in the recirculating lymphocyte pool. The results suggest that neither a massive lymphocyte transfusion nor depletion of the pool by whole body irradiation or chronic lymph drainage affect the rate at which recirculating small lymphocytes are generated.

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