Lymphomas resembling lymphoid leukosis in chickens inoculated with reticuloendotheliosis virus
✍ Scribed by R. L. Witter; L. B. Crittenden
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- French
- Weight
- 635 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
Abstract
Chickens inoculated as embryos or at hatching with the chick syncytial strain of reticuloendo‐theliosis virus developed a high incidence of lymph‐oid neoplasms between the 17th and 43rd weeks of age, involving principally the liver and bursa of Fabricius. On the basis of organ distribution, latent period, pathology and surface IgM production, the lymphomas closely resembled those of lymphoid leukosis. One inoculated chicken developed a myxosarcoma. No tumors were observed in un‐inoculated controls. The tumor‐bearing chickens were free of infection with Marek's disease virus and exogenous avian leukosis virus (ALV) of subgroups A, B, C or D. However, the chickens were known to express endogenous ALV genes to varying degrees.