✦ LIBER ✦

lymphoma type adult T-cell leukemia—a clinicopathologic study of HTLV related T-cell type malignant lymphoma

✍ Scribed by Kazunari Yamaguchi; Ritsuko Yoshioka; Tetsuyuki Kiyokawa; Motoharu Seiki; Mitsuaki Yoshida; Kiyoshi Takatsuki

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 590 KB
Volume: 4
Category: Article
ISSN: 0278-0232
DOI: 10.1002/hon.2900040108

No coin nor oath required. For personal study only.

✦ Synopsis

The clinical and pathological features of T-cell type malignant lymphoma related to human T-cell leukemia virus (HTLV) were investigated in eight patients presenting lymphadenopathy. Biopsy of lymph nodes showed an histology of diffuse non-Hodgkin's lymphoma. All patients were positive for anti-ATLA antibody and HTLV proviral DNA in the lymph node cells. Most patients showed pronounced hypercalcemia and high serum levels of lactic dehydrogenase. All patients died between 3 and 17 months (mean 8 months) after the onset of disease.

HTLV-related malignant lymphoma should be added to the spectrum of ATL, being classified as a lymphoma type ATL.

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