Lymphokine-activated Killer Induction and Its Regulation by Macrophages in Malignant Pleural Effusions
โ Scribed by Yanagawa, Hiroaki ;Sone, Saburo ;Nii, Akihiko ;Fukuta, Katsuyuki ;Nakanishi, Mie ;Maeda, Ken-ichi ;Honda, Mitsuo ;Ogura, Takeshi
- Book ID
- 108578804
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1989
- Tongue
- English
- Weight
- 465 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0910-5050
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Highly purified lymphocytes (> 99%) and monocytes (>90%) were isolated by CCE from peripheral blood of healthy donors. Blood lymphocytes were separated by this CCE into 9 subpopulations. The NK activities of these lymphocyte fractions against NK-sensitive K-562 cells and their LAK activities against
Studies were made to determine whether freshly isolated monocytes from healthy donors could influence the induction of lymphokine (IL-2)-activated killer (LAK) activity. Highly purified lymphocytes (> 99%) and monocytes (> 90ยฐ/o) were isolated by counter-flow centrifugal elutriation from peripheral