Lymphoid cell infiltration into Epstein-Barr virus–positive nasopharyngeal carcinomas
✍ Scribed by Tommy Shpitzer; Jeroen D.F. Kerrebijn; Jeremy L. Freeman; Warren Hartwick; Yuriko Saiki; Jonathan C. Irish; Christina M. Macmillan; Hans-Michael Dosch
- Book ID
- 117843466
- Publisher
- SAGE Publications
- Year
- 2001
- Tongue
- English
- Weight
- 264 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0194-5998
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## Abstract ## Background Little has been known about whether Epstein‐Barr virus (EBV) could persist in nasopharyngeal carcinoma (NPC) cells by chromosomal integration, and no NPC cell line harboring integrated EBV has been reported. In this study, we explored this issue through isolating EBV‐infe
## Abstract Somatic cell hybrids between mouse fibroblasts and human cells derived from nasopharyngeal carcinoma (NPC) biopsies or NPC tumors propagated in nude mice were examined for the expression of the Epstein‐Barr nuclear antigen (EBNA), retention of Epstein‐Barr viral (EBV) DNA, and tumorigen