𝔖 Bobbio Scriptorium
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Lymphocyte subsets alteration in patients with argentine hemorrhagic fever

✍ Scribed by Daniel A. Vallejos; Ana M. Ambrosio; María R. Feuillade; Julio I. Maiztegui

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
363 KB
Volume
27
Category
Article
ISSN
0146-6615

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✦ Synopsis

Peripheral blood lymphocyte subpopulations were studied in 15 patients with Argentine Hemorrhagic Fever (AHF), during the acute period of the disease and in early convalescence. Antihuman lg antibodies were used to identify B cells and monoclonal antibodies t o assess T4 and T8 subsets. During the acute period of the disease, significant alterations were found in B, T4, and T8 lymphocytes ( P < .001), as well as i n T4/T8 ratios ( P < .001). These abnormalities disappeared in early convalescence, around 30 days after the clinical onset. Diminished numbers of T4 lymphocytes are interpreted as relevant to the immunodepression that characterizes the acute phase of AHF.

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