LYMPHOCYTE SENSITIZATION IN SHEEP INOCULATED WITH EXTRACTS OF SPONTANEOUSLY OCCURRING MALIGNANT LYMPHOMAS

Persistent lymphocytosis and virus-like

Persistent lymphocytosis and virus-like particles in lymphocytes of sheep inoculated with cell-free extracts derived from ovine malignant lymphomas

✍ A. C. Johnstone; B. W. Manktelow; R. D. Jolly; D. J. Belton 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 English ⚖ 723 KB

White cell counts of sheep inoculated in utero or at birth with cell-free extracts of ovine malignant lymphomas have been monitored for 5 yr. Of 28 inoculated sheep which have survived, 19 have shown persistent lymphocytosis. After 5 yr, no lymphomas had developed in the inoculated sheep. Electron-m