Lymphocyte recognition of H-2 antigen in liposomes

✍ Scribed by Herrmann, Steven H. ;Mescher, Matthew F.

• Publisher: Wiley (John Wiley & Sons)
• Year: 1981
• Tongue: English
• Weight: 702 KB
• Volume: 16
• Category: Article
• ISSN: 0275-3723
• DOI: 10.1002/jsscb.1981.380160203

✦ Synopsis

Abstract

Liposomes containing purified H‐2K^k^ will specifically stimulate generation of a secondary allogeneic cytolytic T lymphocyte response. Effective recognition was found to depend on the structure of the liposomes. Including detergent‐insoluble plasma membrane matrix during formation resulted in liposomes having two‐ to fourfold more activity than those prepared using just lipid and H‐2.