To investigate the origin of sister chromatid exchanges (SCEs) induced by inhibitors of DNA synthesis, V79/AP4 Chinese hamster cells were treated with aphidicolin, 1-beta-D-arabinofuranosylcytosine, and thymidine. At the end of the treatments we determined both the distribution of the cells in the v
✦ LIBER ✦
Lymphoblasts already in the DNA synthesis phase of the cell cycle can be reversibly arrested at the R/G transition
✍ Scribed by Josée Lavoie; Régen Drouin
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 210 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0009-5915
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## Abstract **Background:** Cell lines that stably over‐express protein kinase C (PKC) δ frequently show a decrease in growth rate and saturation density, leading to the hypothesis that PKCδ has a negative effect on cell proliferation. However, the mode of PKCδ activation, the cell cycle stage requ